The series' single collectible currency of random relics that are left lying around the environments remains. However, there's very little sense of achievement or elation when you discover one, those feelings instead overwhelmed by a greater sense of irritation at the trinkets that you have no doubt missed. There is no reason to play the game twice beyond finding these.
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The execution exhibits a kind of workmanship and polish way beyond the ambition of most other developers, let alone their abilities or budgets. As an expression of all that a video game could be, however, Uncharted 3 is narrow, focused and ultimately shallow. It is a majestic tribute to cinema, a movie game in the literal sense, and your enjoyment will be in precise step with your appreciation of that objective - and whether or not you believe it to be Drake's great deception, or Drake's great delight.